Smith Veterinary Hospital was established in May 1976, when Dr. Larry and Dr. Madge purchased the practice from Deloss Fireoved, DVM. Originally focused on large animals, the clinic consisted of a waiting room, a multi-purpose exam room, a kennel room, an outdoor run, and a big red barn. Drs. Larry and Madge, both Purdue University graduates, had begun working with Dr. Fireoved in 1974 while finishing their veterinary studies, allowing them to get familiar with the practice.

By 1987, the hospital had evolved to serve 60% large animals and 40% small animals. When Dr. Larry attended seminary, Dr. Madge shifted the practice to focus entirely on small animals. After seminary, Dr. Larry returned to practice exclusively in equine medicine.

In 1993-1994, the hospital underwent a major remodel, transforming the exterior with a Berne "Swiss" look and expanding the interior for more hospital space. The current facility includes a large reception area, treatment room, surgery prep room, canine reproduction room, and a companion animal surgery room. The kennel area features stainless steel cages, six indoor runs, and three enclosed outdoor runs. The hospital is equipped with state-of-the-art technology, offering digital radiology, in-house lab work, canine reproduction services, pregnancy ultrasounds, dentistry, and advanced anesthesia and blood pressure monitoring.

In 2018, Dr. Hunt graduated from Purdue University and joined Dr. Madge as a full-time veterinarian. He purchased the practice in early 2020, working alongside Dr. Madge until her retirement in April 2021.